Humans are very new to the field of genetic research, and therefore should not be assumed to be accurate when they present results in genetic research and the resulting Genetically Modified Organisms (GMO) from the new fields of Genetic/Biological Engineering.
The paper, excerpted below, demonstrates the unreliable results of a major tool, Principal Component Analysis (PCA), broadly used in genetic research.
Author: Eran Elhaik, PhD. Population, medical, and evolutionary genomics. Associate Professor at the Department of Biology, Lund University, Sweden
Principal Component Analysis (PCA) is a multivariate analysis that reduces the complexity of datasets while preserving data covariance. The outcome can be visualized on colorful scatterplots, ideally with only a minimal loss of information. PCA applications, implemented in well cited packages like EIGENSOFT and PLINK, are extensively used as the foremost analyses in population genetics and related fields (e.g., animal and plant or medical genetics). PCA outcomes are used to shape study design, identify, and characterize individuals and populations, and draw historical and ethnobiological conclusions on origins, evolution, dispersion, and relatedness. The replicability crisis in science has prompted us to evaluate whether PCA results are reliable, robust, and replicable.
...We demonstrate that PCA results can be artifacts of the data and can be easily manipulated to generate desired outcomes. PCA adjustment also yielded unfavorable outcomes in association studies. PCA results may not be reliable, robust, or replicable as the field assumes. Our findings raise concerns about the validity of results reported in the population genetics literature and related fields that place a disproportionate reliance upon PCA outcomes and the insights derived from them. We conclude that PCA may have a biasing role in genetic investigations and that 32,000 - 216,000 genetic studies should be reevaluated...
Introducing GMOs into the wild/world is akin to people creating and releasing invasive species into the environment...
What could possibly go wrong?
